Benjamin Stecher's Blog

The Futile Hunt for Disease Modifying Therapies

Posted by Benjamin Stecher on 24 May 2019

Disease-modification as a goal of clinical trials is problematic not only because "modification" is an amorphous term, but there is disagreement over the term "disease" itself as we lack a universally accepted definition of Parkinson's disease. Prof. Karl Kieburtz argues that moving to better defined end points would hasten the delivery of better therapeutics for PD. Read more here

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Super Precision Medicine

Posted by Benjamin Stecher on 4 January 2019

Precision therapies are on the horizon, but are they precise enough? The era of precision medicine for Parkinson's disease is fast approaching, but the reality may be that to truly deliver therapies that can help people live better lives we may need to leapfrog the era of precision medicine and jump straight to therapies that are even more precise, aka "super" precision medicine therapies. Read more here

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The GBA-PD Trials: Expert Survey

Posted by Benjamin Stecher on 27 August 2018

The first generation of clinical trials targeting specific genetic subtypes of the Parkinson's population are underway for carriers of GBA and LRRK2 mutations. These trials are among the first attempts to apply principles of precision medicine to a neurodegenerative disease. To gain some clarity, I discussed the current state of GBA-PD research with a range of experts. To read the outcome of this survey, click here

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Putting it all Together: Reflections from Fifty Interviews with World Leading Parkinson’s and Biomedical Experts

Posted by Benjamin Stecher on 11 June 2018

For the past six months, I have been recording and transcribing interviews with a wide variety of Parkinson’s specialists and biomedical researchers. It has been an incredibly enlightening experience that has given me insights into my own journey with Parkinson’s disease, as well as the future of biomedical science. To read my biggest takeaways so far, as well as a selection of meaningful quotes from these experts, click here

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