The Clinical Trial Highlights section of JPD was launched at the start of 2019 and is devoted to raising awareness of the clinical trial landscape in Parkinson’s, promoting discussion and progress in the conduct and outcome of studies. All content in this section is freely available to read, download and share.
You can find in this section of the website (below) an overview of articles published in regular issues of JPD. For details of individual trials, go here or click the visual above. For short extracts of the "Phase 3 Trials in Focus" articles, go here. For a list of Clinical Trials Resources, go here.
To search for specific topics, input free text into the search box at the top right of the website. To fine tune the results, put words in quote marks (e.g. "trial" "dyskinesia").
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Clinical Trial Highlights: Articles
Content included in regular (not all) issues of JPD: listed below with the most recent issue at the top; click the link to be taken to the relevant article published in JPD
JPD Volume 14, Issue 5 (2024)
Parkinson’s Disease Drug Therapies in the Clinical Trial Pipeline: 2024 Update
Research article by Kevin McFarthing, Sue Buff, Gary Rafaloff, Kenneth Pitzer, Brian Fiske, Anaya Navangul, Katelyn Beissert, Aleksandra Pilcicka, Rosie Fuest, Richard K. Wyse and Simon R.W. Stott
JPD Volume 14, Issue 1 (2024)
Clinical Trial Highlights: Dietary Interventions in Parkinson’s Disease
Research article by Indy van der Berg, Sabine Schootemeijer, Karin Overbeek, Bastiaan R. Bloem and Nienke M. de Vries
JPD Volume 13, Issue 6 (2023)
Clinical Trial Highlights: Modulators of Mitochondrial Function
Research article by Francesco Capriglia, Toby Burgess, Oliver Bandmann and Heather Mortiboys
JPD Volume 13, Issue 4 (2023)
Parkinson’s Disease Drug Therapies in the Clinical Trial Pipeline: 2023 Update
Research article by Kevin McFarthing, Susan Buff, Gary Rafaloff, Brian Fiske, Leah Mursaleen, Rosie Fuest, Richard K. Wyse and Simon R.W. Stott
JPD Volume 13, Issue 3 (2023)
Clinical Trial Highlights: Interventions Promoting Physical Activity in Parkinson’s Disease
Research article by Thomas H. Oosterhof, Sabine Schootemeijer and Nienke M. de Vries
JPD Volume 12, Issue 8 (2022)
Clinical Trial Highlights – Aerobic Exercise for Parkinson’s Disease
Research article by Sabine Schootemeijer, Sirwan K.L. Darweesh and Nienke M. de Vries
JPD Volume 12, Issue 4 (2022)
Parkinson’s Disease Drug Therapies in the Clinical Trial Pipeline: 2022 Update
Review article by Kevin McFarthing, Gary Rafaloff, Marco Baptista, Leah Mursaleen, Rosie Fuest, Richard K. Wyse, and Simon R.W. Stott
JPD Volume 12, Issue 2 (2022)
Clinical Trial Highlights – An Update on Previously Reviewed Trials
Clinical Trial Highlights: Phase 3 in Focus – Update (see p.534 in the issue, see PDF)
JPD Volume 11, Issue 3 (2021)
Parkinson’s Disease Drug Therapies in the Clinical Trial Pipeline: 2021 Update
Review article by Kevin McFarthing, Gary Rafaloff, Marco A.S. Baptista, Richard K. Wyse, and Simon R.W. Stott
JPD Volume 11, Issue 2 (2021)
Clinical Trial Highlights – Kinase Inhibitors
Clinical Trial Highlights: Phase 3 in Focus – Ampreloxetine, Theravance Biopharma
JPD Volume 11, Issue 1 (2021)
Clinical Trial Highlights – Parkinson’s Disease Cognition
Clinical Trial Highlights: Phase 3 in Focus – Tavapadon (see p.26 in the issue, see PDF)
JPD Volume 10, Issue 3 (2020)
Parkinson’s Disease Drug Therapies in the Clinical Trial Pipeline: 2020
Research article by Kevin McFarthing, Susan Buff, Gary Rafaloff, Thea Dominey, Richard K. Wyse, and Simon R.W. Stott; view press release here
JPD Volume 10, Issue 2 (2020)
Clinical Trial Highlights: GLP-1 agonists
JPD Volume 10, Issue 1 (2020)
Clinical Trial Highlights: Infusion Therapies
Clinical Trial Highlights: Phase 3 in Focus – Amneal's IPX203 (see p.15 in the PDF)
JPD Volume 9, Issue 3 (2019)
Clinical Trial Highlights: Dyskinesia
Clinical Trial Highlights: Phase 3 in Focus – Adamas Pharma's Gocovri (see p.451 in the PDF)
JPD Volume 9, Issue 2 (2019)
Clinical Trial Highlights: Gene Therapy for Parkinson's
Clinical Trial Highlights: Phase 3 in Focus – Intec Pharma's Accordian Pill (see p.262 in the PDF)
JPD Volume 9, Issue 1 (2019)
Editorial: Introducing Clinical Trials Highlights
Clinical Trials Highlights: Targeting Alpha-Synuclein
Clinical Trials Highlights: Phase 3 in Focus – Israpidene
