JPD Blog

In this section of the JPD blog, Jon Palfreman contributes news of interest to the PD research community, in the form of short opinion items and regular blog posts.

 

13 November 2019

Targeting Alpha-Synuclein in the Gut May Slow Down Parkinson's Disease

Aggregates of the protein alpha-synuclein arising in the gut may play a key role in the development of PD. A new hypothesis relating to alpha-synuclein is being testing and results to date are covered in this review, published in the open access JPD special issue on "The Gut-Brain Axis in Parkinson's Disease".

Interview with Clinical Research Scientist Prof. Karen Raphael

Originally published on Tomorrow Edition on May 31, 2018

Interview With Research Scientist And Communicator Dr. Simon Stott

Originally published on Tomorrow Edition on Nov 30, 2017

Interview With Neuromodulation Expert Dr. Alfonso Fasano

Originally published on Tomorrow Edition on Dec 13, 2017

Interview With Spinal Cord Stimulation Expert Prof. Mandar Jog

Originally published on Tomorrow Edition on May 2, 2019

Genetics in Parkinson's Disease – More Than What You Inherit

Originally published on Tomorrow Edition on June 18, 2019

This is a guest blog post by Hugh Johnston

Last comment on by Leslie Bartnicki,

Interview With Physician-Scientist Prof. Alice Chen-Plotkin

Originally published on Tomorrow Edition on May 21, 2019

Billion Dollar Writing Challenge Winners!

Originally published on Tomorrow Edition on April 9, 2019

The Futile Hunt for Disease Modifying Therapies

Disease-modification as a goal of clinical trials is problematic not only because "modification" is an amorphous term, but there is disagreement over the term "disease" itself as we lack a universally accepted definition of Parkinson's disease. Prof. Karl Kieburtz argues that moving to better defined end points would hasten the delivery of better therapeutics for PD. Read more here

Last comment on by Timothy Welborn...

Cell Replacement Therapy Experts Survey

Originally published on Tomorrow Edition on September 20, 2018

Interview with African Parkinson's Advocate Omotola Thomas

Originally published on Tomorrow Edition on February 16, 2019

Interview with Systems Neurology Expert Prof. Alberto Espay

Originally published on Tomorrow Edition on January 22, 2019

14 February 2019

Can We Repair the Brain? The Promise of Stem Cell Technologies for Treating Parkinson's Disease

Amsterdam, NL – Cell replacement may play an increasing role in alleviating the motor symptoms of Parkinson's disease in future. Writing in a special open access special supplement to the Journal of Parkinson's Disease, experts describe how newly developed stem cell technologies could be used to treat the disease and discuss the great promise, as well as the significant challenges, of stem cell treatment.

12 February 2019

The Search for the Holy Grail: Promising Strategies for Slowing, Stopping, or Reversing Parkinson's Disease

Amsterdam, NL – Understanding of the processes involved in Parkinson's disease (PD) degeneration has vastly improved over the last 20 years. In this insightful review published in an open access special supplement to the Journal of Parkinson's Disease, experts consider which of the existing strategies to slow down or stop the degenerative processes of PD are most likely to be successful over the next 20 years.

7 February 2019

The Involvement of the Gut in Parkinson’s Disease: Hype or Hope?

Amsterdam, NL – There is growing evidence that at least in some patients with Parkinson's disease, the disease may begin in the gut. Writing in an open access special supplement to the Journal of Parkinson's Disease, experts explore the last two decades of research about the gut-brain axis in PD and look ahead at the possible development and impact of these research areas in the next two decades.

The Shaking Shoelace

It is good practice to physically examine patients while being undressed. Here, we illustrate that observation of clothes in dressed patients can occasionally also yield valuable information.

5 February 2019

Experts Propose Revising the Criteria for Diagnosis of Parkinson's Disease with a View Towards Earlier Treatment and Prevention

Amsterdam, NL – In the past 25 years, it has become clear that some symptoms of Parkinson's disease occur decades before the development of motor symptoms and clinical diagnosis, and that monitoring these emerging symptoms may provide important insights into the origin and development of the disease.

Triggers, Facilitators and Aggravators: A New Hypothesis of Parkinson's Disease

Originally published on Tomorrow Edition on October 24, 2018

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